American Airlines
flight
AA 2221:
Multiple routes
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FLIGHT SCHEDULE
Direct Flights:
American Airlines AA2221
Valid until 2026-01-03
Mon
-
-
Tue
-
-
Wed
-
-
Thu
-
-
Fri
-
-
Sat
Sun
-
-
Duration: 1:40, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
-
-
Sun
Duration: 1:37, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-02-12 through 2026-02-21
Mon
-
-
Tue
-
-
Wed
-
-
Thu
Fri
Sat
Sun
-
-
Duration: 1:45, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-02-22 through 2026-03-07
Mon
Tue
-
-
Wed
-
-
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
-
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:27, non-stop
Airbus A319 (319)
Airbus A319 (319)
Direct Flights:
American Airlines AA2221
Effective 2026-02-17 through 2026-03-04
Mon
-
-
Tue
Wed
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:46, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective 2026-03-10 through 2026-03-31
Mon
-
-
Tue
Wed
-
-
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:44, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
-
-
Sun
Duration: 1:43, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-01-08 through 2026-02-09
Mon
Tue
-
-
Wed
-
-
Thu
Fri
Sat
-
-
Sun
Duration: 1:12, non-stop
Airbus A319 (319)
Airbus A319 (319)
Direct Flights:
American Airlines AA2221
Effective 2026-02-12 through 2026-02-21
Mon
-
-
Tue
-
-
Wed
-
-
Thu
Fri
Sat
Sun
-
-
Duration: 1:42, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-02-22 through 2026-03-07
Mon
Tue
-
-
Wed
-
-
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
-
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-02-17 through 2026-03-04
Mon
-
-
Tue
Wed
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:55, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective 2026-03-10 through 2026-03-31
Mon
-
-
Tue
Wed
-
-
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:45, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective 2026-01-11 through 2026-02-08
Mon
-
-
Tue
-
-
Wed
-
-
Thu
-
-
Fri
-
-
Sat
-
-
Sun
Duration: 1:26, non-stop
Airbus A319 (319)
Airbus A319 (319)
Direct Flights:
American Airlines AA2221
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-01-08 through 2026-02-09
Mon
Tue
-
-
Wed
-
-
Thu
Fri
Sat
-
-
Sun
-
-
Duration: 1:26, non-stop
Airbus A319 (319)
Airbus A319 (319)
Direct Flights:
American Airlines AA2221
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:10, non-stop
Airbus A319 (319)
Airbus A319 (319)
Direct Flights:
American Airlines AA2221
Effective 2026-01-06 through 2026-02-03
Mon
-
-
Tue
Wed
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:41, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective 2026-02-10 through 2026-02-11
Mon
-
-
Tue
Wed
Thu
-
-
Fri
-
-
Sat
-
-
Sun
-
-
Duration: 1:41, non-stop
Boeing 737-800 (738)
Boeing 737-800 (738)
Direct Flights:
American Airlines AA2221
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:40, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:35, non-stop
Airbus A321 (321)
Airbus A321 (321)
Direct Flights:
American Airlines AA2221
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 4:32, non-stop
Airbus A321 (321)
Airbus A321 (321)
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Parallax here
This flight number is listed as serving the following routes:
- Atlanta (ATL) - Los Angeles (LAX)
- Indianapolis (IND) - Charlotte (CLT)
- Jacksonville (JAX) - Philadelphia (PHL)
- Norfolk (ORF) - Charlotte (CLT)