American Airlines flight AA 2506: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 09:32 San Francisco (SFO) 1 17:55 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321neo (32Q) 5:23 Effective 2025-10-26 through 2025-11-01
Daily 09:34 San Francisco (SFO) 1 17:55 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321neo (32Q) 5:21 Effective 2026-01-06 through 2026-02-11
Daily 09:38 San Francisco (SFO) 1 17:55 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321neo (32Q) 5:17 Effective 2025-12-03 through 2025-12-17
Daily 09:44 San Francisco (SFO) 1 17:55 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321neo (32Q) 5:11 Effective from 2026-02-12
Daily 14:30 Charlotte (CLT) 16:44 Key West (EYW)
AA 2506 Non-stop Airbus A319 (319) 2:14 Effective 2025-12-18 through 2026-01-05
Daily 17:25 Tampa (TPA) 19:59 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321 (321) 2:34 Valid until 2025-05-04
Daily 17:32 Tampa (TPA) 20:05 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321 (321) 2:33 Effective 2025-08-06 through 2025-09-02
Daily 17:34 Tampa (TPA) 20:10 Philadelphia (PHL)
AA 2506 Non-stop Boeing 737-800 (738) 2:36 Effective 2025-05-05 through 2025-05-22
Fri 17:34 Tampa (TPA) 20:08 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321 (321) 2:34 Operates only on 2025-05-23
Daily 17:34 Tampa (TPA) 20:10 Philadelphia (PHL)
AA 2506 Non-stop Boeing 737-800 (738) 2:36 Effective 2025-05-24 through 2025-06-04
Daily 17:44 Tampa (TPA) 20:20 Philadelphia (PHL)
AA 2506 Non-stop Boeing 737-800 (738) 2:36 Effective 2025-10-06 through 2025-10-25
Daily 17:45 Tampa (TPA) 20:20 Philadelphia (PHL)
AA 2506 Non-stop Airbus A321 (321) 2:35 Effective 2025-09-03 through 2025-10-05
Daily 19:35 Key West (EYW) 21:55 Charlotte (CLT)
AA 2506 Non-stop Airbus A319 (319) 2:20 Effective 2025-12-18 through 2026-01-05
Daily 20:50 Dallas Fort Worth (DFW) 00:16 Jacksonville (JAX)
AA 2506 Non-stop Boeing 737-800 (738) 2:26 Effective 2025-06-05 through 2025-07-03
The flight arrives 1 day after departure.
Mon-Fri 20:51 Dallas Fort Worth (DFW) 00:19 Jacksonville (JAX)
AA 2506 Non-stop Boeing 737-800 (738) 2:28 Effective 2025-07-07 through 2025-08-05
The flight arrives 1 day after departure.
Sat,Sun 20:55 Dallas Fort Worth (DFW) 00:23 Jacksonville (JAX)
AA 2506 Non-stop Boeing 737-800 (738) 2:28 Effective 2025-07-05 through 2025-08-03
The flight arrives 1 day after departure.
Daily 22:30 Miami (MIA) 02:10 Luis Munoz Marin, San Juan (SJU) C
AA 2506 Non-stop Boeing 737-800 (738) 2:40 Effective 2025-11-02 through 2025-12-02
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:


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American Airlines flight AA 2506: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA2506
09:32
San Francisco (SFO) 1

17:55
Philadelphia (PHL)
Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:23, non-stop
Airbus A321neo (32Q)
American Airlines AA2506
09:34
San Francisco (SFO) 1

17:55
Philadelphia (PHL)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:21, non-stop
Airbus A321neo (32Q)
American Airlines AA2506
09:38
San Francisco (SFO) 1

17:55
Philadelphia (PHL)
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:17, non-stop
Airbus A321neo (32Q)
American Airlines AA2506
09:44
San Francisco (SFO) 1

17:55
Philadelphia (PHL)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:11, non-stop
Airbus A321neo (32Q)
American Airlines AA2506
14:30
Charlotte (CLT)

16:44
Key West (EYW)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Airbus A319 (319)
American Airlines AA2506
17:25
Tampa (TPA)

19:59
Philadelphia (PHL)
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:34, non-stop
Airbus A321 (321)
American Airlines AA2506
17:32
Tampa (TPA)

20:05
Philadelphia (PHL)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:33, non-stop
Airbus A321 (321)
American Airlines AA2506
17:34
Tampa (TPA)

20:10
Philadelphia (PHL)
Effective 2025-05-05 through 2025-05-22
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:36, non-stop
Boeing 737-800 (738)
American Airlines AA2506
17:34
Tampa (TPA)

20:08
Philadelphia (PHL)
Operates only on 2025-05-23
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:34, non-stop
Airbus A321 (321)
American Airlines AA2506
17:34
Tampa (TPA)

20:10
Philadelphia (PHL)
Effective 2025-05-24 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:36, non-stop
Boeing 737-800 (738)
American Airlines AA2506
17:44
Tampa (TPA)

20:20
Philadelphia (PHL)
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:36, non-stop
Boeing 737-800 (738)
American Airlines AA2506
17:45
Tampa (TPA)

20:20
Philadelphia (PHL)
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:35, non-stop
Airbus A321 (321)
American Airlines AA2506
19:35
Key West (EYW)

21:55
Charlotte (CLT)
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:20, non-stop
Airbus A319 (319)
American Airlines AA2506
20:50
Dallas Fort Worth (DFW)

00:16(+1)
Jacksonville (JAX)
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:26, non-stop
Boeing 737-800 (738)
The flight arrives 1 day after departure.
American Airlines AA2506
20:51
Dallas Fort Worth (DFW)

00:19(+1)
Jacksonville (JAX)
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:28, non-stop
Boeing 737-800 (738)
The flight arrives 1 day after departure.
American Airlines AA2506
20:55
Dallas Fort Worth (DFW)

00:23(+1)
Jacksonville (JAX)
Effective 2025-07-05 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Duration: 2:28, non-stop
Boeing 737-800 (738)
The flight arrives 1 day after departure.
American Airlines AA2506
22:30
Miami (MIA)

02:10(+1)
Luis Munoz Marin, San Juan (SJU) C
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:40, non-stop
Boeing 737-800 (738)
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:
  • Dallas Fort Worth (DFW) - Jacksonville (JAX)
  • Key West (EYW) - Charlotte (CLT)
  • Miami (MIA) - Luis Munoz Marin, San Juan (SJU)
  • San Francisco (SFO) - Philadelphia (PHL)
  • Tampa (TPA) - Philadelphia (PHL)
All American Airlines flights
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