American Airlines flight AA 4353: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Sun 11:00 New York LaGuardia (LGA) B 12:24 Richmond (RIC)
AA 4353 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2025-06-08 through 2025-06-29
Sun 11:00 New York LaGuardia (LGA) B 12:29 Richmond (RIC)
AA 4353 Non-stop Embraer EMB 175 (E75) 1:29 Effective 2025-07-06 through 2025-08-03
Mon-Fri 11:10 New York LaGuardia (LGA) B 12:32 Richmond (RIC)
AA 4353 Non-stop Embraer EMB 175 (E75) 1:22 Effective 2025-06-05 through 2025-07-03
Mon-Fri 11:10 New York LaGuardia (LGA) B 12:37 Richmond (RIC)
AA 4353 Non-stop Embraer EMB 175 (E75) 1:27 Effective 2025-07-07 through 2025-08-05
Sat 12:06 Norfolk (ORF) 13:30 New York John F. Kennedy (JFK) 8
AA 4353 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2025-05-10 through 2025-05-31
Sat 13:06 Pittsburgh (PIT) 15:59 Miami (MIA)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:53 Effective 2025-07-05 through 2025-08-02
Sat 13:58 Pittsburgh (PIT) 16:39 Miami (MIA)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:41 Effective 2025-06-07 through 2025-06-28
Mon-Fri 14:50 New York LaGuardia (LGA) B 16:17 Nashville (BNA)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:27 Effective 2025-05-05 through 2025-06-04
Sun 15:35 New York LaGuardia (LGA) B 17:14 Nashville (BNA)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:39 Effective 2025-05-11 through 2025-06-01
Daily 15:42 Traverse City (TVC) 16:10 Chicago O'Hare (ORD) 3
AA 4353 Non-stop Embraer EMB 175 (E75) 1:28 Effective 2025-11-02 through 2025-12-02
Daily 18:55 New York LaGuardia (LGA) B 20:47 Saint Louis (STL) 1
AA 4353 Non-stop Embraer EMB 175 (E75) 2:52 Valid until 2025-05-04
Daily 20:20 Chicago O'Hare (ORD) 3 23:00 New Orleans (MSY)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:40 Effective 2025-12-18 through 2026-01-05
Daily 20:20 Chicago O'Hare (ORD) 3 23:02 New Orleans (MSY)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:42 Effective 2026-01-06 through 2026-02-11
Daily 20:26 Ronald Reagan Washington (DCA) 2 22:14 Kansas City (MCI)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:48 Effective 2025-09-03 through 2025-10-05
Daily 20:40 Ronald Reagan Washington (DCA) 2 22:22 Kansas City (MCI)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:42 Effective 2025-08-06 through 2025-09-02
Daily 21:00 Philadelphia (PHL) 23:08 Indianapolis (IND)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:08 Effective 2025-10-06 through 2025-11-01
Daily 21:00 Philadelphia (PHL) 23:11 Indianapolis (IND)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:11 Effective 2025-12-03 through 2025-12-17
Daily 21:00 Philadelphia (PHL) 23:14 Indianapolis (IND)
AA 4353 Non-stop Embraer EMB 175 (E75) 2:14 Effective from 2026-02-12
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This flight number is listed as serving the following routes:
American Airlines flight AA 4353: Multiple routes
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Select flight date:  Show Calendar
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA4353
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:29, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:22, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:27, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-05-10 through 2025-05-31
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:53, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:41, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:27, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-05-11 through 2025-06-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:39, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:28, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:52, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:40, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:42, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:48, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:42, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:11, non-stop
Embraer EMB 175 (E75)

American Airlines AA4353
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:14, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - New Orleans (MSY)
  • New York LaGuardia (LGA) - Nashville (BNA)
  • New York LaGuardia (LGA) - Richmond (RIC)
  • New York LaGuardia (LGA) - Saint Louis (STL)
  • Norfolk (ORF) - New York John F. Kennedy (JFK)
  • Philadelphia (PHL) - Indianapolis (IND)
  • Pittsburgh (PIT) - Miami (MIA)
  • Ronald Reagan Washington (DCA) - Kansas City (MCI)
  • Traverse City (TVC) - Chicago O'Hare (ORD)