American Airlines flight AA 4375: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 07:00 Boston Logan (BOS) B 09:19 John Glenn Columbus (CMH)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:19 Effective 2026-09-09 through 2026-10-04
Daily 08:47 New York LaGuardia (LGA) B 10:05 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:18 Effective 2026-08-05 through 2026-09-08
Daily 10:35 Boston Logan (BOS) B 11:49 New York LaGuardia (LGA) B
AA 4375 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:14 Effective 2026-08-05 through 2026-09-08
Daily 12:00 John Glenn Columbus (CMH) 13:58 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2026-09-09 through 2026-10-04
Daily 12:25 New York LaGuardia (LGA) B 13:35 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:10 Effective 2026-05-21 through 2026-06-03
Daily 12:29 New York LaGuardia (LGA) B 13:39 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:10 Effective 2026-06-04 through 2026-07-01
Sat 12:50 Ronald Reagan Washington (DCA) 2 14:57 Indianapolis (IND)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:07 Effective 2026-02-14 through 2026-03-07
Mon-Fri,Sun 12:50 Ronald Reagan Washington (DCA) 2 14:54 Indianapolis (IND)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:04 Effective 2026-03-08 through 2026-04-06
Sat 12:56 Ronald Reagan Washington (DCA) 2 15:00 Indianapolis (IND)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:04 Effective 2026-03-14 through 2026-04-04
Mon-Fri,Sun 12:59 Ronald Reagan Washington (DCA) 2 15:06 Indianapolis (IND)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:07 Effective 2026-02-12 through 2026-03-06
Daily 13:49 Philadelphia (PHL) 15:15 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2026-01-06 through 2026-02-11
Daily 14:11 Boston Logan (BOS) B 15:30 New York LaGuardia (LGA) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:19 Effective 2026-06-04 through 2026-07-01
Daily 14:15 Boston Logan (BOS) B 15:34 New York LaGuardia (LGA) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:19 Effective 2026-05-21 through 2026-06-03
Daily 14:45 New York LaGuardia (LGA) B 16:05 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:20 Effective 2026-04-07 through 2026-05-20
Sat 15:28 Indianapolis (IND) 17:19 Ronald Reagan Washington (DCA) 2
AA 4375 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2026-02-14 through 2026-03-07
Mon-Fri,Sun 15:28 Indianapolis (IND) 17:14 Ronald Reagan Washington (DCA) 2
AA 4375 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2026-03-08 through 2026-04-06
Sat 15:33 Indianapolis (IND) 17:19 Ronald Reagan Washington (DCA) 2
AA 4375 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2026-03-14 through 2026-04-04
Daily 15:35 Philadelphia (PHL) 16:59 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:24 Effective 2026-07-02 through 2026-08-04
Mon-Fri,Sun 15:36 Indianapolis (IND) 17:27 Ronald Reagan Washington (DCA) 2
AA 4375 Non-stop Embraer EMB 175 (E75) 1:51 Effective 2026-02-12 through 2026-03-06
Sat 16:33 Chicago O'Hare (ORD) 3 17:43 Madison (MSN)
AA 4375 Non-stop Embraer EMB 175 (E75) 1:10 Operates only on 2026-01-03
Daily 16:35 Boston Logan (BOS) B 17:53 New York LaGuardia (LGA) B
AA 4375 Non-stop Embraer EMB 175 (E75) 1:18 Effective 2026-04-07 through 2026-05-20
Mon,Tue,Thu,Fri,Sun 16:38 Chicago O'Hare (ORD) 3 17:47 Madison (MSN)
AA 4375 Non-stop Embraer EMB 175 (E75) 1:09 Valid until 2026-01-05
Daily 16:55 John Glenn Columbus (CMH) 18:55 Boston Logan (BOS) B
AA 4375 Non-stop Embraer EMB 175 (E75) 2:00 Effective from 2026-10-05
Sat 18:14 Madison (MSN) 19:46 Chicago O'Hare (ORD) 3
AA 4375 Non-stop Embraer EMB 175 (E75) 1:32 Operates only on 2026-01-03
Mon,Tue,Thu,Fri,Sun 18:18 Madison (MSN) 19:41 Chicago O'Hare (ORD) 3
AA 4375 Non-stop Embraer EMB 175 (E75) 1:23 Valid until 2026-01-05
Daily 18:41 Boston Logan (BOS) B 20:25 Philadelphia (PHL)
AA 4375 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2026-07-02 through 2026-08-04
Daily 19:25 Boston Logan (BOS) B 21:44 John Glenn Columbus (CMH)
AA 4375 Non-stop Embraer EMB 175 (E75) 2:19 Effective from 2026-10-05
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This flight number is listed as serving the following routes:
American Airlines flight AA 4375: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA4375
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:18, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4375
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:14, non-stop
Embraer EMB 170 / EMB 175 (E70)

Direct Flights:

American Airlines AA4375
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-05-21 through 2026-06-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-06-04 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:07, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:04, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:04, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:07, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-06-04 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:19, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-05-21 through 2026-06-03
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:19, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:20, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:51, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:46, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:24, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-02-12 through 2026-03-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:51, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Operates only on 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:10, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:09, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Operates only on 2026-01-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:32, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:23, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4375
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:19, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - New York LaGuardia (LGA)
  • John Glenn Columbus (CMH) - Boston Logan (BOS)
  • Madison (MSN) - Chicago O'Hare (ORD)
  • Philadelphia (PHL) - Boston Logan (BOS)
  • Ronald Reagan Washington (DCA) - Indianapolis (IND)