American Airlines flight AA 4443: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 06:59 New York LaGuardia (LGA) B 08:44 Saint Louis (STL) 1
AA 4443 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2026-08-05 through 2026-09-08
Daily 09:40 Chicago O'Hare (ORD) 3 11:49 Indianapolis (IND)
AA 4443 Non-stop Embraer EMB 175 (E75) 1:09 Effective 2026-05-21 through 2026-07-01
Mon-Fri,Sun 10:00 New York John F. Kennedy (JFK) 8 12:00 John Glenn Columbus (CMH)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2026-03-08 through 2026-04-06
Daily 10:24 Saint Louis (STL) 1 13:53 New York LaGuardia (LGA) B
AA 4443 Non-stop Embraer EMB 175 (E75) 2:29 Effective 2026-08-05 through 2026-09-08
Sat 10:30 New York John F. Kennedy (JFK) 8 12:30 John Glenn Columbus (CMH)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2026-03-14 through 2026-04-04
Daily 12:20 Indianapolis (IND) 12:40 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 1:20 Effective 2026-05-21 through 2026-07-01
Mon-Fri,Sun 12:30 John Glenn Columbus (CMH) 14:27 New York John F. Kennedy (JFK) 8
AA 4443 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2026-03-08 through 2026-04-06
Daily 12:47 Key West (EYW) 15:54 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:07 Effective 2026-02-13 through 2026-03-07
Thu 12:55 Key West (EYW) 16:02 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:07 Operates only on 2026-02-12
Sat 13:00 John Glenn Columbus (CMH) 14:57 New York John F. Kennedy (JFK) 8
AA 4443 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2026-03-14 through 2026-04-04
Daily 13:10 Chicago O'Hare (ORD) 3 15:59 Houston George Bush (IAH) A
AA 4443 Non-stop Embraer EMB 175 (E75) 2:49 Effective 2026-07-02 through 2026-08-04
Mon-Fri,Sun 14:00 Key West (EYW) 17:05 Philadelphia (PHL)
AA 4443 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2026-01-06 through 2026-02-11
Mon,Tue,Thu-Sun 14:28 Chicago O'Hare (ORD) 3 17:57 Jacksonville (JAX)
AA 4443 Non-stop Embraer EMB 175 (E75) 2:29 Valid until 2026-01-05
Daily 15:23 Nashville (BNA) 18:59 New York John F. Kennedy (JFK) 8
AA 4443 Non-stop Embraer EMB 175 (E75) 2:36 Effective from 2026-10-05
Daily 16:40 Houston George Bush (IAH) A 19:50 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 3:10 Effective 2026-07-02 through 2026-08-04
Mon,Tue,Thu-Sun 18:27 Jacksonville (JAX) 20:30 Chicago O'Hare (ORD) 3
AA 4443 Non-stop Embraer EMB 175 (E75) 3:03 Valid until 2026-01-05
Daily 22:00 Ronald Reagan Washington (DCA) 2 23:45 Columbia (CAE)
AA 4443 Non-stop Embraer EMB 175 (E75) 1:45 Effective 2026-09-09 through 2026-10-04
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4443: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4443
06:59
New York LaGuardia (LGA) B

08:44
Saint Louis (STL) 1
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:45, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
09:40
Chicago O'Hare (ORD) 3

11:49
Indianapolis (IND)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:09, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
10:00
New York John F. Kennedy (JFK) 8

12:00
John Glenn Columbus (CMH)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
10:24
Saint Louis (STL) 1

13:53
New York LaGuardia (LGA) B
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
10:30
New York John F. Kennedy (JFK) 8

12:30
John Glenn Columbus (CMH)
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
12:20
Indianapolis (IND)

12:40
Chicago O'Hare (ORD) 3
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:20, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
12:30
John Glenn Columbus (CMH)

14:27
New York John F. Kennedy (JFK) 8
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
12:47
Key West (EYW)

15:54
Philadelphia (PHL)
Effective 2026-02-13 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:07, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
12:55
Key West (EYW)

16:02
Philadelphia (PHL)
Operates only on 2026-02-12
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 3:07, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
13:00
John Glenn Columbus (CMH)

14:57
New York John F. Kennedy (JFK) 8
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
13:10
Chicago O'Hare (ORD) 3

15:59
Houston George Bush (IAH) A
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:49, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
14:00
Key West (EYW)

17:05
Philadelphia (PHL)
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 3:05, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
14:28
Chicago O'Hare (ORD) 3

17:57
Jacksonville (JAX)
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:29, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
15:23
Nashville (BNA)

18:59
New York John F. Kennedy (JFK) 8
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:36, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
16:40
Houston George Bush (IAH) A

19:50
Chicago O'Hare (ORD) 3
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:10, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
18:27
Jacksonville (JAX)

20:30
Chicago O'Hare (ORD) 3
Valid until 2026-01-05
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 3:03, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4443
22:00
Ronald Reagan Washington (DCA) 2

23:45
Columbia (CAE)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Houston George Bush (IAH)
  • Chicago O'Hare (ORD) - Indianapolis (IND)
  • Chicago O'Hare (ORD) - Jacksonville (JAX)
  • John Glenn Columbus (CMH) - New York John F. Kennedy (JFK)
  • Key West (EYW) - Philadelphia (PHL)
  • Nashville (BNA) - New York John F. Kennedy (JFK)
  • Ronald Reagan Washington (DCA) - Columbia (CAE)
  • Saint Louis (STL) - New York LaGuardia (LGA)
All American Airlines flights
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