American Airlines flight AA 4458: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Mon 06:54 Cleveland Hopkins (CLE) 08:30 New York LaGuardia (LGA) B
AA 4458 Non-stop Embraer EMB 175 (E75) 1:36 Operates only on 2025-05-05
Daily 07:29 Ronald Reagan Washington (DCA) 2 09:06 Saint Louis (STL) 1
AA 4458 Non-stop Embraer EMB 175 (E75) 2:37 Effective 2025-12-03 through 2025-12-17
Daily 07:58 Ronald Reagan Washington (DCA) 2 09:29 Saint Louis (STL) 1
AA 4458 Non-stop Embraer EMB 175 (E75) 2:31 Effective 2025-11-02 through 2025-12-02
Daily 08:00 Cleveland Hopkins (CLE) 09:26 Philadelphia (PHL)
AA 4458 Non-stop Embraer EMB 175 (E75) 1:26 Effective 2025-05-20 through 2025-06-04
Daily 08:10 Ronald Reagan Washington (DCA) 2 09:54 Saint Louis (STL) 1
AA 4458 Non-stop Embraer EMB 175 (E75) 2:44 Effective 2026-01-06 through 2026-02-11
Daily 08:15 Ronald Reagan Washington (DCA) 2 09:56 Saint Louis (STL) 1
AA 4458 Non-stop Embraer EMB 175 (E75) 2:41 Effective 2025-12-18 through 2026-01-05
Daily 09:51 Saint Louis (STL) 1 12:59 Ronald Reagan Washington (DCA) 2
AA 4458 Non-stop Embraer EMB 175 (E75) 2:08 Effective 2025-12-03 through 2025-12-17
Daily 09:59 Saint Louis (STL) 1 12:59 Ronald Reagan Washington (DCA) 2
AA 4458 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2025-11-02 through 2025-12-02
Daily 10:38 Saint Louis (STL) 1 13:42 Ronald Reagan Washington (DCA) 2
AA 4458 Non-stop Embraer EMB 175 (E75) 2:04 Effective 2025-12-18 through 2026-01-05
Daily 10:40 Saint Louis (STL) 1 13:45 Ronald Reagan Washington (DCA) 2
AA 4458 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2026-01-06 through 2026-02-11
Daily 11:00 New York LaGuardia (LGA) B 13:12 Indianapolis (IND)
AA 4458 Non-stop Embraer EMB 175 (E75) 2:12 Effective 2025-08-06 through 2025-09-02
Sat 12:39 Louisville (SDF) 15:18 Miami (MIA)
AA 4458 Non-stop Embraer EMB 175 (E75) 2:39 Effective 2025-07-05 through 2025-08-02
Sat 12:44 Louisville (SDF) 15:20 Miami (MIA)
AA 4458 Non-stop Embraer EMB 175 (E75) 2:36 Effective 2025-06-07 through 2025-06-28
Daily 17:15 Ronald Reagan Washington (DCA) 2 18:23 Nashville (BNA)
AA 4458 Non-stop Embraer EMB 175 (E75) 2:08 Effective 2025-10-06 through 2025-11-01
Daily 19:39 Nashville (BNA) 22:29 Ronald Reagan Washington (DCA) 2
AA 4458 Non-stop Embraer EMB 175 (E75) 1:50 Effective 2025-10-06 through 2025-11-01
Mon-Fri,Sun 20:46 New York LaGuardia (LGA) B 23:09 Indianapolis (IND)
AA 4458 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:23 Effective 2025-07-06 through 2025-08-05
Mon-Fri 21:00 New York LaGuardia (LGA) B 23:16 Indianapolis (IND)
AA 4458 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:16 Effective 2025-06-05 through 2025-07-03
Sun 21:09 New York LaGuardia (LGA) B 23:25 Indianapolis (IND)
AA 4458 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:16 Effective 2025-06-08 through 2025-06-29
Daily 22:10 Chicago O'Hare (ORD) 3 23:50 Minneapolis/Saint Paul (MSP) 1
AA 4458 Non-stop Embraer EMB 175 (E75) 1:40 Effective 2025-09-03 through 2025-10-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4458: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4458
06:54
Cleveland Hopkins (CLE)

08:30
New York LaGuardia (LGA) B
Operates only on 2025-05-05
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
07:29
Ronald Reagan Washington (DCA) 2

09:06
Saint Louis (STL) 1
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:37, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
07:58
Ronald Reagan Washington (DCA) 2

09:29
Saint Louis (STL) 1
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:31, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
08:00
Cleveland Hopkins (CLE)

09:26
Philadelphia (PHL)
Effective 2025-05-20 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
08:10
Ronald Reagan Washington (DCA) 2

09:54
Saint Louis (STL) 1
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:44, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
08:15
Ronald Reagan Washington (DCA) 2

09:56
Saint Louis (STL) 1
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:41, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
09:51
Saint Louis (STL) 1

12:59
Ronald Reagan Washington (DCA) 2
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
09:59
Saint Louis (STL) 1

12:59
Ronald Reagan Washington (DCA) 2
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
10:38
Saint Louis (STL) 1

13:42
Ronald Reagan Washington (DCA) 2
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:04, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
10:40
Saint Louis (STL) 1

13:45
Ronald Reagan Washington (DCA) 2
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
11:00
New York LaGuardia (LGA) B

13:12
Indianapolis (IND)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:12, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
12:39
Louisville (SDF)

15:18
Miami (MIA)
Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:39, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
12:44
Louisville (SDF)

15:20
Miami (MIA)
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
17:15
Ronald Reagan Washington (DCA) 2

18:23
Nashville (BNA)
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
19:39
Nashville (BNA)

22:29
Ronald Reagan Washington (DCA) 2
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:50, non-stop
Embraer EMB 175 (E75)
American Airlines AA4458
20:46
New York LaGuardia (LGA) B

23:09
Indianapolis (IND)
Effective 2025-07-06 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:23, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4458
21:00
New York LaGuardia (LGA) B

23:16
Indianapolis (IND)
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:16, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4458
21:09
New York LaGuardia (LGA) B

23:25
Indianapolis (IND)
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:16, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4458
22:10
Chicago O'Hare (ORD) 3

23:50
Minneapolis/Saint Paul (MSP) 1
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Chicago O'Hare (ORD) - Minneapolis/Saint Paul (MSP)
  • Cleveland Hopkins (CLE) - New York LaGuardia (LGA)
  • Cleveland Hopkins (CLE) - Philadelphia (PHL)
  • Louisville (SDF) - Miami (MIA)
  • Nashville (BNA) - Ronald Reagan Washington (DCA)
  • New York LaGuardia (LGA) - Indianapolis (IND)
  • Ronald Reagan Washington (DCA) - Saint Louis (STL)
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