American Airlines flight AA 4521: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Mon-Fri,Sun 05:30 Nashville (BNA) 07:28 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 1:58 Valid until 2026-01-05
Thu 06:13 Hartford (BDL) 08:20 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 3:07 Operates only on 2026-02-12
Sat 07:18 Nashville (BNA) 09:14 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 1:56 Valid until 2026-01-03
Daily 08:25 Pittsburgh (PIT) 09:10 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 1:45 Effective 2026-09-09 through 2026-10-04
Daily 12:58 New York LaGuardia (LGA) B 14:45 Saint Louis (STL) 1 AA 4521 Non-stop Embraer EMB 175 (E75) 2:47 Effective 2026-04-07 through 2026-05-20
Daily 13:03 Chicago O'Hare (ORD) 3 16:20 Hartford (BDL) AA 4521 Non-stop Embraer EMB 175 (E75) 2:17 Effective 2026-01-06 through 2026-02-11
Mon-Fri 13:11 Chicago O'Hare (ORD) 3 16:30 Hartford (BDL) AA 4521 Non-stop Embraer EMB 175 (E75) 2:19 Effective 2026-03-09 through 2026-04-06
Sat 13:32 Chicago O'Hare (ORD) 3 16:51 Hartford (BDL) AA 4521 Non-stop Embraer EMB 175 (E75) 2:19 Effective 2026-03-14 through 2026-04-04
Sun 14:17 Chicago O'Hare (ORD) 3 17:35 Hartford (BDL) AA 4521 Non-stop Embraer EMB 175 (E75) 2:18 Effective 2026-03-08 through 2026-04-05
Daily 16:32 Saint Louis (STL) 1 20:00 New York LaGuardia (LGA) B AA 4521 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2026-04-07 through 2026-05-20
Daily 16:50 Hartford (BDL) 18:55 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2026-01-06 through 2026-01-16
Daily 16:50 Hartford (BDL) 18:55 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2026-01-18 through 2026-02-11
Mon-Sat 17:59 Hartford (BDL) 20:05 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 3:06 Effective 2026-03-09 through 2026-04-06
Sun 18:05 Hartford (BDL) 20:10 Chicago O'Hare (ORD) 3 AA 4521 Non-stop Embraer EMB 175 (E75) 3:05 Effective 2026-03-08 through 2026-04-05
Daily 20:29 New York LaGuardia (LGA) B 22:03 Buffalo (BUF) AA 4521 Non-stop Embraer EMB 175 (E75) 1:34 Effective 2026-05-21 through 2026-07-01
Daily 20:29 New York LaGuardia (LGA) B 22:08 Buffalo (BUF) AA 4521 Non-stop Embraer EMB 175 (E75) 1:39 Effective 2026-07-02 through 2026-08-04
Daily 20:29 New York LaGuardia (LGA) B 22:05 Buffalo (BUF) AA 4521 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:36 Effective 2026-08-05 through 2026-09-08

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This flight number is listed as serving the following routes:

Hartford (BDL) - Chicago O'Hare (ORD)
Nashville (BNA) - Chicago O'Hare (ORD)
New York LaGuardia (LGA) - Buffalo (BUF)
Pittsburgh (PIT) - Chicago O'Hare (ORD)
Saint Louis (STL) - New York LaGuardia (LGA)

All American Airlines flights

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American Airlines flight AA 4521: Multiple routes

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FLIGHT SCHEDULE

Direct Flights:

American Airlines AA4521

05:30

Nashville (BNA)

07:28

Chicago O'Hare (ORD) 3

Valid until 2026-01-05

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun

Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

06:13

Hartford (BDL)

08:20

Chicago O'Hare (ORD) 3

Operates only on 2026-02-12

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Duration: 3:07, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

07:18

Nashville (BNA)

09:14

Chicago O'Hare (ORD) 3

Valid until 2026-01-03

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 1:56, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

08:25

Pittsburgh (PIT)

09:10

Chicago O'Hare (ORD) 3

Effective 2026-09-09 through 2026-10-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:45, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

12:58

New York LaGuardia (LGA) B

14:45

Saint Louis (STL) 1

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:47, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

13:03

Chicago O'Hare (ORD) 3

16:20

Hartford (BDL)

Effective 2026-01-06 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:17, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

13:11

Chicago O'Hare (ORD) 3

16:30

Hartford (BDL)

Effective 2026-03-09 through 2026-04-06

Mon

Tue

Wed

Thu

Fri

Sat
-

Sun
-

Duration: 2:19, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

13:32

Chicago O'Hare (ORD) 3

16:51

Hartford (BDL)

Effective 2026-03-14 through 2026-04-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Duration: 2:19, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

14:17

Chicago O'Hare (ORD) 3

17:35

Hartford (BDL)

Effective 2026-03-08 through 2026-04-05

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 2:18, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

16:32

Saint Louis (STL) 1

20:00

New York LaGuardia (LGA) B

Effective 2026-04-07 through 2026-05-20

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 2:28, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

16:50

Hartford (BDL)

18:55

Chicago O'Hare (ORD) 3

Effective 2026-01-06 through 2026-01-16

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:05, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

16:50

Hartford (BDL)

18:55

Chicago O'Hare (ORD) 3

Effective 2026-01-18 through 2026-02-11

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 3:05, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

17:59

Hartford (BDL)

20:05

Chicago O'Hare (ORD) 3

Effective 2026-03-09 through 2026-04-06

Mon

Tue

Wed

Thu

Fri

Sat

Sun
-

Duration: 3:06, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

18:05

Hartford (BDL)

20:10

Chicago O'Hare (ORD) 3

Effective 2026-03-08 through 2026-04-05

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Duration: 3:05, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

20:29

New York LaGuardia (LGA) B

22:03

Buffalo (BUF)

Effective 2026-05-21 through 2026-07-01

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:34, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

20:29

New York LaGuardia (LGA) B

22:08

Buffalo (BUF)

Effective 2026-07-02 through 2026-08-04

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:39, non-stop
Embraer EMB 175 (E75)

Direct Flights:

American Airlines AA4521

20:29

New York LaGuardia (LGA) B

22:05

Buffalo (BUF)

Effective 2026-08-05 through 2026-09-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun

Duration: 1:36, non-stop
Embraer EMB 170 / EMB 175 (E70)

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Parallax here

This flight number is listed as serving the following routes:

Hartford (BDL) - Chicago O'Hare (ORD)
Nashville (BNA) - Chicago O'Hare (ORD)
New York LaGuardia (LGA) - Buffalo (BUF)
Pittsburgh (PIT) - Chicago O'Hare (ORD)
Saint Louis (STL) - New York LaGuardia (LGA)

All American Airlines flights

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