American Airlines flight AA 4597: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 07:03 Indianapolis (IND) 07:30 Chicago O'Hare (ORD) 3
AA 4597 Non-stop Embraer EMB 175 (E75) 1:27 Effective 2026-05-21 through 2026-07-01
Daily 07:11 Indianapolis (IND) 07:30 Chicago O'Hare (ORD) 3
AA 4597 Non-stop Embraer EMB 175 (E75) 1:19 Effective 2026-07-02 through 2026-08-04
Daily 07:31 Ronald Reagan Washington (DCA) 2 10:43 Key West (EYW)
AA 4597 Non-stop Embraer EMB 175 (E75) 3:12 Valid until 2026-01-05
Sun 08:01 Ronald Reagan Washington (DCA) 2 11:23 Key West (EYW)
AA 4597 Non-stop Embraer EMB 175 (E75) 3:22 Effective 2026-02-15 through 2026-03-01
Daily 09:29 New York LaGuardia (LGA) B 11:23 John Glenn Columbus (CMH)
AA 4597 Non-stop Embraer EMB 175 (E75) 1:54 Effective 2026-04-07 through 2026-05-20
Sat 15:35 New York LaGuardia (LGA) B 17:15 Madison (MSN)
AA 4597 Non-stop Embraer EMB 175 (E75) 2:40 Effective 2026-03-14 through 2026-04-04
Mon-Fri,Sun 21:02 New York LaGuardia (LGA) B 22:42 Madison (MSN)
AA 4597 Non-stop Embraer EMB 175 (E75) 2:40 Effective 2026-03-08 through 2026-04-06
Daily 22:00 Ronald Reagan Washington (DCA) 2 23:30 Buffalo (BUF)
AA 4597 Non-stop Embraer EMB 175 (E75) 1:30 Effective 2026-08-05 through 2026-09-08
Daily 22:00 Ronald Reagan Washington (DCA) 2 23:26 Buffalo (BUF)
AA 4597 Non-stop Embraer EMB 175 (E75) 1:26 Effective from 2026-10-05
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4597: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4597
07:03
Indianapolis (IND)

07:30
Chicago O'Hare (ORD) 3
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:27, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
07:11
Indianapolis (IND)

07:30
Chicago O'Hare (ORD) 3
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:19, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
07:31
Ronald Reagan Washington (DCA) 2

10:43
Key West (EYW)
Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 3:12, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
08:01
Ronald Reagan Washington (DCA) 2

11:23
Key West (EYW)
Effective 2026-02-15 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 3:22, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
09:29
New York LaGuardia (LGA) B

11:23
John Glenn Columbus (CMH)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
15:35
New York LaGuardia (LGA) B

17:15
Madison (MSN)
Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:40, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
21:02
New York LaGuardia (LGA) B

22:42
Madison (MSN)
Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:40, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
22:00
Ronald Reagan Washington (DCA) 2

23:30
Buffalo (BUF)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:30, non-stop
Embraer EMB 175 (E75)
Direct Flights:
American Airlines AA4597
22:00
Ronald Reagan Washington (DCA) 2

23:26
Buffalo (BUF)
Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:26, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Indianapolis (IND) - Chicago O'Hare (ORD)
  • New York LaGuardia (LGA) - John Glenn Columbus (CMH)
  • New York LaGuardia (LGA) - Madison (MSN)
  • Ronald Reagan Washington (DCA) - Buffalo (BUF)
  • Ronald Reagan Washington (DCA) - Key West (EYW)
All American Airlines flights
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