American Airlines flight AA 4649: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 07:30 Nashville (BNA) 10:06 Raleigh/Durham (RDU) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2025-09-03 through 2025-10-05
Sat 14:05 New York LaGuardia (LGA) B 15:47 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:42 Valid until 2025-05-03
Sun 14:30 New York LaGuardia (LGA) B 16:10 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:40 Valid until 2025-05-04
Mon-Thu 14:40 New York LaGuardia (LGA) B 16:18 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:38 Valid until 2025-05-01
Sat,Sun 14:59 Ronald Reagan Washington (DCA) 2 16:44 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:45 Effective 2025-06-21 through 2025-06-29
Sat 14:59 Ronald Reagan Washington (DCA) 2 16:45 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2025-07-05 through 2025-08-02
Mon-Fri,Sun 15:03 Ronald Reagan Washington (DCA) 2 16:49 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:46 Effective 2025-07-06 through 2025-08-05
Daily 15:19 Ronald Reagan Washington (DCA) 2 17:02 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:43 Effective 2025-08-06 through 2025-09-02
Mon-Fri 15:20 Ronald Reagan Washington (DCA) 2 16:56 Nantucket (ACK)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:36 Effective 2025-06-19 through 2025-07-03
Sun 16:20 New York LaGuardia (LGA) B 17:52 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 175 (E75) 1:32 Effective 2025-05-11 through 2025-06-01
Mon-Fri 16:25 New York LaGuardia (LGA) B 17:57 Pittsburgh (PIT)
AA 4649 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:32 Effective 2025-05-05 through 2025-06-04
Daily 16:30 Ronald Reagan Washington (DCA) 2 18:04 Boston Logan (BOS) B
AA 4649 Non-stop Embraer EMB 175 (E75) 1:34 Effective 2026-01-07 through 2026-02-11
Mon-Thu 17:05 Pittsburgh (PIT) 18:29 New York LaGuardia (LGA) B
AA 4649 Non-stop Embraer EMB 175 (E75) 1:24 Valid until 2025-05-01
Sat 17:16 Nantucket (ACK) 19:00 Ronald Reagan Washington (DCA) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2025-06-21 through 2025-06-28
Daily 17:19 Nantucket (ACK) 19:04 Ronald Reagan Washington (DCA) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:45 Effective 2025-07-05 through 2025-08-05
Mon-Fri,Sun 17:26 Nantucket (ACK) 19:10 Ronald Reagan Washington (DCA) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:44 Effective 2025-06-19 through 2025-07-03
Daily 17:33 Nantucket (ACK) 19:15 Ronald Reagan Washington (DCA) 2
AA 4649 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2025-08-06 through 2025-09-02
Mon-Fri 18:52 Pittsburgh (PIT) 20:15 New York LaGuardia (LGA) B
AA 4649 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:23 Effective 2025-05-05 through 2025-06-04
Sun 18:52 Pittsburgh (PIT) 20:15 New York LaGuardia (LGA) B
AA 4649 Non-stop Embraer EMB 175 (E75) 1:23 Effective 2025-05-11 through 2025-06-01
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4649: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4649
07:30
Nashville (BNA)

10:06
Raleigh/Durham (RDU) 2
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
14:05
New York LaGuardia (LGA) B

15:47
Pittsburgh (PIT)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
14:30
New York LaGuardia (LGA) B

16:10
Pittsburgh (PIT)
Valid until 2025-05-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:40, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
14:40
New York LaGuardia (LGA) B

16:18
Pittsburgh (PIT)
Valid until 2025-05-01
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:38, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
14:59
Ronald Reagan Washington (DCA) 2

16:44
Nantucket (ACK)
Effective 2025-06-21 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
Duration: 1:45, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
14:59
Ronald Reagan Washington (DCA) 2

16:45
Nantucket (ACK)
Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
15:03
Ronald Reagan Washington (DCA) 2

16:49
Nantucket (ACK)
Effective 2025-07-06 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:46, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
15:19
Ronald Reagan Washington (DCA) 2

17:02
Nantucket (ACK)
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
15:20
Ronald Reagan Washington (DCA) 2

16:56
Nantucket (ACK)
Effective 2025-06-19 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:36, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
16:20
New York LaGuardia (LGA) B

17:52
Pittsburgh (PIT)
Effective 2025-05-11 through 2025-06-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:32, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
16:25
New York LaGuardia (LGA) B

17:57
Pittsburgh (PIT)
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:32, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4649
16:30
Ronald Reagan Washington (DCA) 2

18:04
Boston Logan (BOS) B
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
17:05
Pittsburgh (PIT)

18:29
New York LaGuardia (LGA) B
Valid until 2025-05-01
Mon
Tue
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:24, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
17:16
Nantucket (ACK)

19:00
Ronald Reagan Washington (DCA) 2
Effective 2025-06-21 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:44, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
17:19
Nantucket (ACK)

19:04
Ronald Reagan Washington (DCA) 2
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
17:26
Nantucket (ACK)

19:10
Ronald Reagan Washington (DCA) 2
Effective 2025-06-19 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:44, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
17:33
Nantucket (ACK)

19:15
Ronald Reagan Washington (DCA) 2
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
American Airlines AA4649
18:52
Pittsburgh (PIT)

20:15
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:23, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4649
18:52
Pittsburgh (PIT)

20:15
New York LaGuardia (LGA) B
Effective 2025-05-11 through 2025-06-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:23, non-stop
Embraer EMB 175 (E75)
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This flight number is listed as serving the following routes:
  • Nashville (BNA) - Raleigh/Durham (RDU)
  • New York LaGuardia (LGA) - Pittsburgh (PIT)
  • Ronald Reagan Washington (DCA) - Boston Logan (BOS)
  • Ronald Reagan Washington (DCA) - Nantucket (ACK)
All American Airlines flights
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