American Airlines flight AA 5421: Multiple routes

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FLIGHT SCHEDULE
Direct Flights:
Daily 05:12 Moline (MLI) 08:20 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:08 Effective 2026-04-07 through 2026-05-20
Daily 05:13 Moline (MLI) 08:20 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:07 Effective 2026-05-21 through 2026-07-01
Daily 06:15 Moline (MLI) 09:45 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:30 Effective 2026-01-07 through 2026-02-11
Daily 07:07 Moline (MLI) 10:25 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:18 Effective 2026-09-09 through 2026-10-04
Daily 07:10 Moline (MLI) 10:20 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:10 Effective 2026-08-05 through 2026-09-08
Daily 07:12 Moline (MLI) 10:25 Charlotte (CLT)
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:13 Effective 2026-07-02 through 2026-08-04
Sun 20:47 Birmingham (BHM) 23:05 Chicago O'Hare (ORD) 3
AA 5421 Non-stop Canadair CRJ 900 (CR9) 2:18 Operates only on 2026-01-04
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5421: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5421
05:12
Moline (MLI)

08:20
Charlotte (CLT)
Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
05:13
Moline (MLI)

08:20
Charlotte (CLT)
Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:07, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
06:15
Moline (MLI)

09:45
Charlotte (CLT)
Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:30, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
07:07
Moline (MLI)

10:25
Charlotte (CLT)
Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:18, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
07:10
Moline (MLI)

10:20
Charlotte (CLT)
Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:10, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
07:12
Moline (MLI)

10:25
Charlotte (CLT)
Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Canadair CRJ 900 (CR9)
Direct Flights:
American Airlines AA5421
20:47
Birmingham (BHM)

23:05
Chicago O'Hare (ORD) 3
Operates only on 2026-01-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:18, non-stop
Canadair CRJ 900 (CR9)
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This flight number is listed as serving the following routes:
  • Birmingham (BHM) - Chicago O'Hare (ORD)
  • Moline (MLI) - Charlotte (CLT)
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