American Airlines flight AA 646: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 10:40 Philadelphia (PHL) 13:02 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:22 Effective 2025-09-03 through 2025-10-05
Mon-Sat 10:44 Philadelphia (PHL) 12:46 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:02 Effective 2025-06-05 through 2025-06-14
Mon-Sat 10:44 Philadelphia (PHL) 12:46 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:02 Effective 2025-06-23 through 2025-07-04
Daily 10:45 Philadelphia (PHL) 13:08 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:23 Valid until 2025-05-04
Sun 10:45 Philadelphia (PHL) 12:51 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:06 Effective 2025-07-06 through 2025-08-03
Sun 10:46 Philadelphia (PHL) 12:48 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:02 Effective 2025-06-08 through 2025-06-15
Daily 10:46 Philadelphia (PHL) 12:48 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:02 Effective 2025-06-16 through 2025-06-22
Sun 10:46 Philadelphia (PHL) 12:48 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:02 Operates only on 2025-06-29
Mon-Sat 10:50 Philadelphia (PHL) 12:59 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:09 Effective 2025-07-05 through 2025-08-05
Daily 10:55 Philadelphia (PHL) 13:10 Phoenix Sky Harbor (PHX) 4
AA 646 Non-stop Airbus A321neo (32Q) 5:15 Effective 2025-05-05 through 2025-06-04
Daily 16:08 Los Angeles (LAX) 17:18 Las Vegas Harry Reid (LAS) 1
AA 646 Non-stop Boeing 737-800 (738) 1:10 Effective 2025-08-06 through 2025-09-02
Daily 18:35 Philadelphia (PHL) 21:13 Orlando (MCO) B
AA 646 Non-stop Airbus A321 (321) 2:38 Effective 2025-10-06 through 2025-10-25
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This flight number is listed as serving the following routes:
American Airlines flight AA 646: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

American Airlines AA646
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:22, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-06-05 through 2025-06-14
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 5:02, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-06-23 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 5:02, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:23, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 5:06, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-06-08 through 2025-06-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 5:02, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-06-16 through 2025-06-22
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:02, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Operates only on 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 5:02, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 5:09, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 5:15, non-stop
Airbus A321neo (32Q)

American Airlines AA646
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:10, non-stop
Boeing 737-800 (738)

American Airlines AA646
Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:38, non-stop
Airbus A321 (321)
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This flight number is listed as serving the following routes:
  • Los Angeles (LAX) - Las Vegas Harry Reid (LAS)
  • Philadelphia (PHL) - Orlando (MCO)
  • Philadelphia (PHL) - Phoenix Sky Harbor (PHX)