Azores Airlines flight S4 8486: Lisbon - Brussels

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FLIGHT SCHEDULE
Direct Codeshare Flights:
Mon,Wed,Fri,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-10-26 through 2025-11-03 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2025-10-28 through 2025-11-04 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Thu,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2025-10-30 through 2025-11-05 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu-Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-11-06 through 2025-11-10 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2025-11-11 through 2025-11-15 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Operates only on 2025-11-12 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu,Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2025-11-13 through 2025-11-14 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Tue,Thu,Sat,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-11-16 through 2025-11-22 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2025-11-19 through 2025-12-02 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Effective 2025-11-23 through 2025-11-30 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2025-11-24 through 2025-11-29 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-12-01 through 2025-12-06 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Operates only on 2025-12-03 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Wed-Fri,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2025-12-04 through 2025-12-10 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Tue,Thu,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-12-09 through 2025-12-15 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu,Fri,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2025-12-12 through 2025-12-19 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Operates only on 2025-12-16 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon-Wed,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-12-17 through 2025-12-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Operates only on 2025-12-20 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Thu 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2025-12-25 through 2025-12-30 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Wed-Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2025-12-26 through 2026-01-01 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2026-01-02 through 2026-01-09 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Wed,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-01-03 through 2026-01-07 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Operates only on 2026-01-04 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Thu,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2026-01-06 through 2026-01-10 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-01-11 through 2026-01-18 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Operates only on 2026-01-12 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu-Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2026-01-15 through 2026-01-23 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2026-01-20 through 2026-01-25 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-01-21 through 2026-01-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon-Wed,Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2026-01-26 through 2026-01-30 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2026-01-29 through 2026-01-31 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-02-01 through 2026-02-02 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Effective 2026-02-03 through 2026-02-10 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu,Sat,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Effective 2026-02-05 through 2026-02-08 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Wed,Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2026-02-06 through 2026-02-11 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-02-12 through 2026-02-19 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Operates only on 2026-02-13 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Operates only on 2026-02-14 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective 2026-02-15 through 2026-02-18 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Tue,Fri,Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:50 Effective 2026-02-20 through 2026-02-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sun 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:50 Operates only on 2026-02-22 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:50 Operates only on 2026-02-25 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Thu-Sat 20:00 Lisbon (LIS) 1 23:50 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:50 Effective from 2026-02-26 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Valid until 2025-05-01 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon-Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-05-02 through 2025-05-08 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-05-04 through 2025-05-09 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-05-10 through 2025-05-15 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Fri,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-05-12 through 2025-05-19 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Effective 2025-05-18 through 2025-05-25 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Fri,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-05-20 through 2025-05-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-05-22 through 2025-05-26 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Operates only on 2025-05-27 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-05-28 through 2025-06-05 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-05-30 through 2025-06-01 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Fri,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-06-06 through 2025-06-14 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:45 Operates only on 2025-06-08 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-06-15 through 2025-06-20 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Operates only on 2025-06-18 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:45 Effective 2025-06-21 through 2025-06-22 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-06-24 through 2025-06-29 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Effective 2025-06-25 through 2025-07-02 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Thu 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-06-26 through 2025-07-03 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-07-05 through 2025-07-12 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Effective 2025-07-13 through 2025-07-16 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-07-15 through 2025-07-22 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Effective 2025-07-23 through 2025-07-26 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-07-27 through 2025-08-05 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Operates only on 2025-08-06 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-08-07 through 2025-08-14 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-08-15 through 2025-09-05 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Thu,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-08-16 through 2025-08-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Operates only on 2025-08-19 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-08-26 through 2025-09-02 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Operates only on 2025-09-03 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-09-06 through 2025-09-13 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-09-07 through 2025-09-12 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Wed,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-09-14 through 2025-09-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-09-19 through 2025-09-26 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Fri-Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-09-27 through 2025-10-03 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue,Thu,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-09-30 through 2025-10-05 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Operates only on 2025-10-07 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-10-08 through 2025-10-14 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Wed,Fri,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:45 Effective 2025-10-10 through 2025-10-17 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Tue-Thu,Sat,Sun 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Effective 2025-10-16 through 2025-10-23 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:45 Operates only on 2025-10-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Sat 20:10 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A319 (319) 2:45 Operates only on 2025-10-25 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Effective 2025-06-02 through 2025-06-30 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Effective 2025-06-12 through 2025-06-19 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Fri 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Effective 2025-07-04 through 2025-07-07 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Effective 2025-07-10 through 2025-07-24 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:40 Operates only on 2025-07-11 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Fri 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Effective 2025-07-14 through 2025-07-18 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:40 Operates only on 2025-07-21 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Fri 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Effective 2025-07-25 through 2025-08-01 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Effective 2025-07-28 through 2025-07-31 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Effective 2025-08-04 through 2025-09-15 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Thu 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Effective 2025-09-04 through 2025-09-18 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon,Thu 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Effective 2025-09-22 through 2025-09-29 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320 (320) 2:40 Operates only on 2025-10-06 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A321neo (32Q) 2:40 Operates only on 2025-10-13 Codeshare flight, operated by TAP Air Portugal.(TP 646)
Mon 20:15 Lisbon (LIS) 1 23:55 Brussels (BRU) S4 8486 Non-stop Airbus A320neo (32N) 2:40 Operates only on 2025-10-20 Codeshare flight, operated by TAP Air Portugal.(TP 646)

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S4 8486 is an international flight departing from Lisbon airport, Portugal (LIS) and arriving at Brussels airport, Belgium (BRU).
The flight distance is 1066 miles, or 1716 km.
The timezone of the departure airport is UTC+0 (plus 1h DST), and the timezone of the arrival airport is UTC+1 (plus 1h DST). Current time at the point of departure is 6:41am, and 7:41am at the point of arrival. There is a 1 hour time difference between the airports.
For direct flights, the flight time varies between 2:40 and 2:50.

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Azores Airlines flight S4 8486:
Lisbon - Brussels

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FLIGHT SCHEDULE

Direct Codeshare Flights:

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-10-26 through 2025-11-03

Mon

Tue
-

Wed

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-10-28 through 2025-11-04

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-10-30 through 2025-11-05

Mon
-

Tue
-

Wed

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-06 through 2025-11-10

Mon

Tue
-

Wed
-

Thu

Fri

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-11 through 2025-11-15

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2025-11-12

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-13 through 2025-11-14

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-16 through 2025-11-22

Mon

Tue

Wed
-

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-19 through 2025-12-02

Mon
-

Tue

Wed

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-23 through 2025-11-30

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-11-24 through 2025-11-29

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-01 through 2025-12-06

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2025-12-03

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-04 through 2025-12-10

Mon

Tue
-

Wed

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-09 through 2025-12-15

Mon

Tue

Wed
-

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-12 through 2025-12-19

Mon
-

Tue
-

Wed
-

Thu

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2025-12-16

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-17 through 2025-12-24

Mon

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2025-12-20

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-25 through 2025-12-30

Mon
-

Tue

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2025-12-26 through 2026-01-01

Mon

Tue
-

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-02 through 2026-01-09

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-03 through 2026-01-07

Mon

Tue
-

Wed

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-01-04

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-06 through 2026-01-10

Mon
-

Tue

Wed
-

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-11 through 2026-01-18

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-01-12

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-15 through 2026-01-23

Mon

Tue
-

Wed
-

Thu

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-20 through 2026-01-25

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-21 through 2026-01-24

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-26 through 2026-01-30

Mon

Tue

Wed

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-01-29 through 2026-01-31

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-01 through 2026-02-02

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-03 through 2026-02-10

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-05 through 2026-02-08

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-06 through 2026-02-11

Mon

Tue
-

Wed

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-12 through 2026-02-19

Mon

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-02-13

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-02-14

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-15 through 2026-02-18

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective 2026-02-20 through 2026-02-24

Mon

Tue

Wed
-

Thu
-

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-02-22

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Operates only on 2026-02-25

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:00

Lisbon (LIS) 1

23:50

Brussels (BRU)

Effective from 2026-02-26

Mon
-

Tue

Wed
-

Thu

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:50, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Valid until 2025-05-01

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-02 through 2025-05-08

Mon

Tue

Wed

Thu

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-04 through 2025-05-09

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-10 through 2025-05-15

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-12 through 2025-05-19

Mon

Tue
-

Wed
-

Thu
-

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-18 through 2025-05-25

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-20 through 2025-05-24

Mon
-

Tue

Wed

Thu
-

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-22 through 2025-05-26

Mon

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-05-27

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-28 through 2025-06-05

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-05-30 through 2025-06-01

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-06 through 2025-06-14

Mon
-

Tue

Wed

Thu
-

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-06-08

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-15 through 2025-06-20

Mon
-

Tue

Wed
-

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-06-18

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-21 through 2025-06-22

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-24 through 2025-06-29

Mon
-

Tue

Wed
-

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-25 through 2025-07-02

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-26 through 2025-07-03

Mon
-

Tue

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-05 through 2025-07-12

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-13 through 2025-07-16

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-15 through 2025-07-22

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-23 through 2025-07-26

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-27 through 2025-08-05

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-08-06

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-08-07 through 2025-08-14

Mon
-

Tue

Wed

Thu

Fri

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-08-15 through 2025-09-05

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-08-16 through 2025-08-24

Mon
-

Tue
-

Wed

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-08-19

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-08-26 through 2025-09-02

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-09-03

Mon
-

Tue
-

Wed

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-06 through 2025-09-13

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-07 through 2025-09-12

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-14 through 2025-09-24

Mon
-

Tue

Wed

Thu
-

Fri
-

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-19 through 2025-09-26

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-27 through 2025-10-03

Mon
-

Tue
-

Wed

Thu
-

Fri

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-30 through 2025-10-05

Mon
-

Tue

Wed
-

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-07

Mon
-

Tue

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-10-08 through 2025-10-14

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-10-10 through 2025-10-17

Mon
-

Tue
-

Wed

Thu
-

Fri

Sat
-

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-10-16 through 2025-10-23

Mon
-

Tue

Wed

Thu

Fri
-

Sat

Sun

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-24

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:10

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-25

Mon
-

Tue
-

Wed
-

Thu
-

Fri
-

Sat

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:45, non-stop
Airbus A319 (319)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-02 through 2025-06-30

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-06-12 through 2025-06-19

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-04 through 2025-07-07

Mon

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-10 through 2025-07-24

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-07-11

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-14 through 2025-07-18

Mon

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-07-21

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-25 through 2025-08-01

Mon
-

Tue
-

Wed
-

Thu
-

Fri

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-07-28 through 2025-07-31

Mon

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-08-04 through 2025-09-15

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-04 through 2025-09-18

Mon
-

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Effective 2025-09-22 through 2025-09-29

Mon

Tue
-

Wed
-

Thu

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-06

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320 (320)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-13

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A321neo (32Q)

Azores Airlines S48486

20:15

Lisbon (LIS) 1

23:55

Brussels (BRU)

Operates only on 2025-10-20

Mon

Tue
-

Wed
-

Thu
-

Fri
-

Sat
-

Sun
-

Codeshare flight, operated by TAP Air Portugal. (TP 646)

Duration: 2:40, non-stop
Airbus A320neo (32N)

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Parallax here LIS-BRU

S4 8486 is an international flight departing from Lisbon airport, Portugal (LIS) and arriving at Brussels airport, Belgium (BRU).
The flight distance is 1066 miles, or 1716 km.
The timezone of the departure airport is UTC+0 (plus 1h DST), and the timezone of the arrival airport is UTC+1 (plus 1h DST). Current time at the point of departure is 6:41am, and 7:41am at the point of arrival. There is a 1 hour time difference between the airports.
For direct flights, the flight time varies between 2:40 and 2:50.

All Azores Airlines flights

All LIS-BRU flights

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