American Airlines flights from Knoxville (TYS) to New York LaGuardia (LGA).

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Sun 09:44 Knoxville (TYS) 11:49 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2025-06-08 through 2025-06-29
Sun 09:47 Knoxville (TYS) 11:49 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:02 Effective 2025-07-06 through 2025-08-03
Daily 11:30 Knoxville (TYS) 13:29 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2025-09-03 through 2025-10-05
Tue,Fri 11:54 Knoxville (TYS) 13:57 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:03 Valid until 2025-05-02
Mon-Fri 11:55 Knoxville (TYS) 14:00 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:05 Effective 2025-06-05 through 2025-07-03
Mon-Fri 11:55 Knoxville (TYS) 13:59 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:04 Effective 2025-07-07 through 2025-08-05
Mon,Wed,Thu,Sun 12:00 Knoxville (TYS) 14:03 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:03 Valid until 2025-05-04
Sat 12:00 Knoxville (TYS) 14:03 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:03 Valid until 2025-05-03
Mon-Fri,Sun 12:02 Knoxville (TYS) 13:59 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective 2025-05-05 through 2025-06-04
Sat 12:16 Knoxville (TYS) 14:20 New York LaGuardia (LGA) B
American Airlines AA 4413 Non-stop Embraer EMB 175 (E75) 2:04 Effective 2025-06-07 through 2025-06-21
Daily 11:04 Knoxville (TYS) 12:59 New York LaGuardia (LGA) B
American Airlines AA 4541 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-11-02 through 2025-12-02
Daily 11:09 Knoxville (TYS) 13:07 New York LaGuardia (LGA) B
American Airlines AA 4541 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-12-03 through 2025-12-17
Daily 11:21 Knoxville (TYS) 13:19 New York LaGuardia (LGA) B
American Airlines AA 4541 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2026-01-06 through 2026-02-11
Daily 11:38 Knoxville (TYS) 13:33 New York LaGuardia (LGA) B
American Airlines AA 4541 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-12-18 through 2026-01-05
Daily 12:03 Knoxville (TYS) 14:00 New York LaGuardia (LGA) B
American Airlines AA 4541 Non-stop Embraer EMB 175 (E75) 1:57 Effective from 2026-02-12
Daily 06:25 Knoxville (TYS) 08:23 New York LaGuardia (LGA) B
American Airlines AA 4576 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2026-01-06 through 2026-02-11
Daily 06:26 Knoxville (TYS) 08:23 New York LaGuardia (LGA) B
American Airlines AA 4576 Non-stop Embraer EMB 175 (E75) 1:57 Effective from 2026-02-12
Daily 06:30 Knoxville (TYS) 08:28 New York LaGuardia (LGA) B
American Airlines AA 4576 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-12-03 through 2025-12-17
Daily 06:33 Knoxville (TYS) 08:29 New York LaGuardia (LGA) B
American Airlines AA 4576 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2025-11-02 through 2025-12-02
Daily 06:34 Knoxville (TYS) 08:29 New York LaGuardia (LGA) B
American Airlines AA 4576 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-12-18 through 2026-01-05
Mon-Fri 05:33 Knoxville (TYS) 07:37 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:04 Effective 2025-07-07 through 2025-08-05
Thu 05:39 Knoxville (TYS) 07:44 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 175 (E75) 2:05 Operates only on 2025-06-05
Mon-Fri 05:39 Knoxville (TYS) 07:44 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:05 Effective 2025-06-06 through 2025-07-03
Mon-Fri 06:10 Knoxville (TYS) 08:07 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2025-05-05 through 2025-06-04
Mon-Fri,Sun 06:17 Knoxville (TYS) 08:20 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 175 (E75) 2:03 Valid until 2025-05-04
Daily 06:30 Knoxville (TYS) 08:29 New York LaGuardia (LGA) B
American Airlines AA 4675 Non-stop Embraer EMB 175 (E75) 1:59 Effective 2025-09-03 through 2025-10-05
Daily 16:21 Knoxville (TYS) 18:29 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 2:08 Effective 2025-08-06 through 2025-09-02
Daily 16:32 Knoxville (TYS) 18:29 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 1:57 Effective 2025-10-06 through 2025-11-01
Mon-Fri,Sun 16:57 Knoxville (TYS) 19:01 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:04 Effective 2025-07-06 through 2025-08-05
Mon-Fri,Sun 17:14 Knoxville (TYS) 19:19 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:05 Effective 2025-06-06 through 2025-07-03
Thu 17:24 Knoxville (TYS) 19:29 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:05 Operates only on 2025-06-05
Mon-Fri 17:30 Knoxville (TYS) 19:33 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 2:03 Valid until 2025-05-02
Sun 17:30 Knoxville (TYS) 19:33 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 2:03 Valid until 2025-05-04
Daily 17:35 Knoxville (TYS) 19:30 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-12-18 through 2026-01-05
Daily 17:37 Knoxville (TYS) 19:35 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2026-01-06 through 2026-02-11
Daily 17:39 Knoxville (TYS) 19:30 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:51 Effective from 2026-02-12
Mon-Fri,Sun 17:51 Knoxville (TYS) 19:48 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective 2025-05-05 through 2025-06-04
Daily 18:00 Knoxville (TYS) 20:00 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 2:00 Effective 2025-09-03 through 2025-10-05
Daily 18:25 Knoxville (TYS) 20:21 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2025-11-02 through 2025-12-02
Daily 18:31 Knoxville (TYS) 20:29 New York LaGuardia (LGA) B
American Airlines AA 4761 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-12-03 through 2025-12-17
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American Airlines flights from Knoxville (TYS) to New York LaGuardia (LGA).
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4413
09:44
Knoxville (TYS)

11:49
New York LaGuardia (LGA) B
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
09:47
Knoxville (TYS)

11:49
New York LaGuardia (LGA) B
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:02, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
11:30
Knoxville (TYS)

13:29
New York LaGuardia (LGA) B
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
11:54
Knoxville (TYS)

13:57
New York LaGuardia (LGA) B
Valid until 2025-05-02
Mon
-
Tue
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:03, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4413
11:55
Knoxville (TYS)

14:00
New York LaGuardia (LGA) B
Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
11:55
Knoxville (TYS)

13:59
New York LaGuardia (LGA) B
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:04, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
12:00
Knoxville (TYS)

14:03
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4413
12:00
Knoxville (TYS)

14:03
New York LaGuardia (LGA) B
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
American Airlines AA4413
12:02
Knoxville (TYS)

13:59
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4413
12:16
Knoxville (TYS)

14:20
New York LaGuardia (LGA) B
Effective 2025-06-07 through 2025-06-21
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:04, non-stop
Embraer EMB 175 (E75)
American Airlines AA4541
11:04
Knoxville (TYS)

12:59
New York LaGuardia (LGA) B
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
American Airlines AA4541
11:09
Knoxville (TYS)

13:07
New York LaGuardia (LGA) B
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4541
11:21
Knoxville (TYS)

13:19
New York LaGuardia (LGA) B
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4541
11:38
Knoxville (TYS)

13:33
New York LaGuardia (LGA) B
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
American Airlines AA4541
12:03
Knoxville (TYS)

14:00
New York LaGuardia (LGA) B
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4576
06:25
Knoxville (TYS)

08:23
New York LaGuardia (LGA) B
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4576
06:26
Knoxville (TYS)

08:23
New York LaGuardia (LGA) B
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4576
06:30
Knoxville (TYS)

08:28
New York LaGuardia (LGA) B
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4576
06:33
Knoxville (TYS)

08:29
New York LaGuardia (LGA) B
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)
American Airlines AA4576
06:34
Knoxville (TYS)

08:29
New York LaGuardia (LGA) B
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
American Airlines AA4675
05:33
Knoxville (TYS)

07:37
New York LaGuardia (LGA) B
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:04, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4675
05:39
Knoxville (TYS)

07:44
New York LaGuardia (LGA) B
Operates only on 2025-06-05
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 175 (E75)
American Airlines AA4675
05:39
Knoxville (TYS)

07:44
New York LaGuardia (LGA) B
Effective 2025-06-06 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4675
06:10
Knoxville (TYS)

08:07
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4675
06:17
Knoxville (TYS)

08:20
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
American Airlines AA4675
06:30
Knoxville (TYS)

08:29
New York LaGuardia (LGA) B
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
16:21
Knoxville (TYS)

18:29
New York LaGuardia (LGA) B
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:08, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
16:32
Knoxville (TYS)

18:29
New York LaGuardia (LGA) B
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
16:57
Knoxville (TYS)

19:01
New York LaGuardia (LGA) B
Effective 2025-07-06 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:04, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
17:14
Knoxville (TYS)

19:19
New York LaGuardia (LGA) B
Effective 2025-06-06 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
17:24
Knoxville (TYS)

19:29
New York LaGuardia (LGA) B
Operates only on 2025-06-05
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:05, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
17:30
Knoxville (TYS)

19:33
New York LaGuardia (LGA) B
Valid until 2025-05-02
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:03, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
17:30
Knoxville (TYS)

19:33
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:03, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
17:35
Knoxville (TYS)

19:30
New York LaGuardia (LGA) B
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
17:37
Knoxville (TYS)

19:35
New York LaGuardia (LGA) B
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
17:39
Knoxville (TYS)

19:30
New York LaGuardia (LGA) B
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:51, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
17:51
Knoxville (TYS)

19:48
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)
American Airlines AA4761
18:00
Knoxville (TYS)

20:00
New York LaGuardia (LGA) B
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
18:25
Knoxville (TYS)

20:21
New York LaGuardia (LGA) B
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)
American Airlines AA4761
18:31
Knoxville (TYS)

20:29
New York LaGuardia (LGA) B
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)
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Parallax here TYS-LGA
  • A domestic route departing from the Knoxville airport (TYS) and arriving at New York LaGuardia airport (LGA).
  • The flight distance is 646 miles, or 1040 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 1:51 and 2:08.
All TYS-LGA flights
All American Airlines flights
Return (LGA-TYS) flights
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