American Airlines flights from Knoxville (TYS) to Chicago O'Hare (ORD).

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FLIGHT SCHEDULE
Direct Flights:
Daily 11:45 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 3472 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-10-26 through 2025-11-01
Daily 11:45 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 3633 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-10-06 through 2025-10-25
Daily 08:13 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
American Airlines AA 3909 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective from 2026-02-12
Daily 18:51 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 4052 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:59 Effective 2026-01-06 through 2026-02-11
Daily 18:52 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 4052 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-12-18 through 2026-01-05
Daily 18:53 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 4052 Non-stop Embraer EMB 170 / EMB 175 (E70) 1:57 Effective 2025-12-03 through 2025-12-17
Daily 20:19 Knoxville (TYS) 21:15 Chicago O'Hare (ORD) 3
American Airlines AA 4342 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2025-10-26 through 2025-11-01
Daily 20:19 Knoxville (TYS) 21:15 Chicago O'Hare (ORD) 3
American Airlines AA 4473 Non-stop Embraer EMB 175 (E75) 1:56 Effective 2025-10-06 through 2025-10-25
Mon-Fri,Sun 13:54 Knoxville (TYS) 14:56 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 2:02 Effective 2025-07-06 through 2025-08-08
Daily 13:54 Knoxville (TYS) 14:56 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 2:02 Effective 2025-08-09 through 2025-10-05
Mon-Fri,Sun 13:56 Knoxville (TYS) 14:54 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-06-05 through 2025-07-03
Sat 14:50 Knoxville (TYS) 15:48 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 1:58 Effective 2025-06-07 through 2025-06-28
Sat 14:57 Knoxville (TYS) 15:59 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 2:02 Effective 2025-07-05 through 2025-08-02
Fri 15:01 Knoxville (TYS) 15:59 Chicago O'Hare (ORD) 3
American Airlines AA 4536 Non-stop Embraer EMB 175 (E75) 1:58 Operates only on 2025-07-04
Daily 11:45 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 4600 Non-stop Embraer EMB 175 (E75) 1:55 Effective 2025-12-03 through 2026-01-05
Daily 13:01 Knoxville (TYS) 13:59 Chicago O'Hare (ORD) 3
American Airlines AA 5105 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-07-05 through 2025-08-05
Daily 13:06 Knoxville (TYS) 13:59 Chicago O'Hare (ORD) 3
American Airlines AA 5105 Non-stop Canadair CRJ 700 (CR7) 1:53 Effective 2025-06-05 through 2025-07-04
Daily 05:20 Knoxville (TYS) 06:15 Chicago O'Hare (ORD) 3
American Airlines AA 5110 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-10-26 through 2025-11-01
Daily 13:01 Knoxville (TYS) 13:59 Chicago O'Hare (ORD) 3
American Airlines AA 5117 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-08-06 through 2025-09-02
Daily 13:25 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5119 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-10-26 through 2025-11-01
Daily 18:39 Knoxville (TYS) 19:37 Chicago O'Hare (ORD) 3
American Airlines AA 5143 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-09-03 through 2025-10-05
Daily 10:16 Knoxville (TYS) 11:10 Chicago O'Hare (ORD) 3
American Airlines AA 5155 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2025-11-02 through 2025-12-02
Daily 13:25 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5172 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-10-06 through 2025-10-25
Daily 18:39 Knoxville (TYS) 19:37 Chicago O'Hare (ORD) 3
American Airlines AA 5178 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-08-06 through 2025-09-02
Daily 13:26 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2026-01-07 through 2026-02-11
Daily 18:54 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 5181 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective 2025-11-02 through 2025-12-02
Daily 11:46 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 5185 Non-stop Canadair CRJ 700 (CR7) 1:54 Effective 2025-11-02 through 2025-12-02
Daily 05:20 Knoxville (TYS) 06:15 Chicago O'Hare (ORD) 3
American Airlines AA 5195 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-10-06 through 2025-10-25
Daily 13:01 Knoxville (TYS) 13:59 Chicago O'Hare (ORD) 3
American Airlines AA 5202 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-09-03 through 2025-10-05
Daily 18:50 Knoxville (TYS) 19:50 Chicago O'Hare (ORD) 3
American Airlines AA 5217 Non-stop Canadair CRJ 700 (CR7) 2:00 Effective from 2026-02-12
Daily 11:44 Knoxville (TYS) 12:40 Chicago O'Hare (ORD) 3
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:56 Effective from 2026-02-12
Sun 18:37 Knoxville (TYS) 19:35 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-07-06 through 2025-08-03
Daily 18:39 Knoxville (TYS) 19:34 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-06-05 through 2025-06-30
Wed,Thu 18:39 Knoxville (TYS) 19:34 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:55 Effective 2025-07-02 through 2025-07-03
Mon-Sat 18:39 Knoxville (TYS) 19:37 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:58 Effective 2025-07-05 through 2025-08-05
Tue 18:40 Knoxville (TYS) 19:35 Chicago O'Hare (ORD) 3
American Airlines AA 5302 Non-stop Canadair CRJ 700 (CR7) 1:55 Operates only on 2025-07-01
Tue 13:26 Knoxville (TYS) 14:20 Chicago O'Hare (ORD) 3
American Airlines AA 5348 Non-stop Canadair CRJ 700 (CR7) 1:54 Operates only on 2026-01-06
Mon-Fri,Sun 08:05 Knoxville (TYS) 09:09 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2025-06-05 through 2025-07-04
Sat 08:06 Knoxville (TYS) 09:10 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 2:04 Effective 2025-06-07 through 2025-06-28
Daily 08:06 Knoxville (TYS) 09:05 Chicago O'Hare (ORD) 3
American Airlines AA 5379 Non-stop Canadair CRJ 700 (CR7) 1:59 Effective 2025-07-05 through 2025-10-05
Daily 15:00 Knoxville (TYS) 16:02 Chicago O'Hare (ORD) 3
American Airlines AA 5684 Non-stop Embraer ERJ 145 (ER4) 2:02 Effective 2025-05-05 through 2025-06-04
Daily 15:09 Knoxville (TYS) 16:16 Chicago O'Hare (ORD) 3
American Airlines AA 5722 Non-stop Embraer ERJ 145 (ER4) 2:07 Valid until 2025-05-04
Daily 19:50 Knoxville (TYS) 20:53 Chicago O'Hare (ORD) 3
American Airlines AA 5722 Non-stop Embraer ERJ 145 (ER4) 2:03 Effective 2025-05-05 through 2025-05-23
Daily 19:50 Knoxville (TYS) 20:53 Chicago O'Hare (ORD) 3
American Airlines AA 5722 Non-stop Embraer ERJ 145 (ER4) 2:03 Effective 2025-05-25 through 2025-06-04
Daily 05:05 Knoxville (TYS) 06:08 Chicago O'Hare (ORD) 3
American Airlines AA 5735 Non-stop Embraer ERJ 145 (ER4) 2:03 Effective 2025-05-05 through 2025-05-24
Daily 05:05 Knoxville (TYS) 06:08 Chicago O'Hare (ORD) 3
American Airlines AA 5735 Non-stop Embraer ERJ 145 (ER4) 2:03 Effective 2025-05-26 through 2025-06-04
Daily 05:15 Knoxville (TYS) 06:22 Chicago O'Hare (ORD) 3
American Airlines AA 5742 Non-stop Embraer ERJ 145 (ER4) 2:07 Valid until 2025-05-04
Mon,Wed-Fri,Sun 11:43 Knoxville (TYS) 12:49 Chicago O'Hare (ORD) 3
American Airlines AA 5743 Non-stop Embraer ERJ 145 (ER4) 2:06 Valid until 2025-05-04
Tue,Sat 12:32 Knoxville (TYS) 13:39 Chicago O'Hare (ORD) 3
American Airlines AA 5743 Non-stop Embraer ERJ 145 (ER4) 2:07 Valid until 2025-05-03
Mon,Wed-Fri,Sun 20:07 Knoxville (TYS) 21:14 Chicago O'Hare (ORD) 3
American Airlines AA 5748 Non-stop Embraer ERJ 145 (ER4) 2:07 Valid until 2025-05-04
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American Airlines flights from Knoxville (TYS) to Chicago O'Hare (ORD).
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)

Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)

Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)

Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Embraer EMB 170 / EMB 175 (E70)

Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:57, non-stop
Embraer EMB 170 / EMB 175 (E70)

Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)

Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Embraer EMB 175 (E75)

Effective 2025-07-06 through 2025-08-08
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:02, non-stop
Embraer EMB 175 (E75)

Effective 2025-08-09 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:02, non-stop
Embraer EMB 175 (E75)

Effective 2025-06-05 through 2025-07-03
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:02, non-stop
Embraer EMB 175 (E75)

Operates only on 2025-07-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 1:58, non-stop
Embraer EMB 175 (E75)

Effective 2025-12-03 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Embraer EMB 175 (E75)

Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-10-26 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective 2026-01-07 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-10-06 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:00, non-stop
Canadair CRJ 700 (CR7)

Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:56, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-06-05 through 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-07-02 through 2025-07-03
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 1:58, non-stop
Canadair CRJ 700 (CR7)

Operates only on 2025-07-01
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:55, non-stop
Canadair CRJ 700 (CR7)

Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:54, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-06-05 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:04, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-07-05 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:59, non-stop
Canadair CRJ 700 (CR7)

Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:02, non-stop
Embraer ERJ 145 (ER4)

Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:07, non-stop
Embraer ERJ 145 (ER4)

Effective 2025-05-05 through 2025-05-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer ERJ 145 (ER4)

Effective 2025-05-25 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer ERJ 145 (ER4)

Effective 2025-05-05 through 2025-05-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer ERJ 145 (ER4)

Effective 2025-05-26 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:03, non-stop
Embraer ERJ 145 (ER4)

Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:07, non-stop
Embraer ERJ 145 (ER4)

Valid until 2025-05-04
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:06, non-stop
Embraer ERJ 145 (ER4)

Valid until 2025-05-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:07, non-stop
Embraer ERJ 145 (ER4)

Valid until 2025-05-04
Mon
Tue
-
Wed
Thu
Fri
Sat
-
Sun
Duration: 2:07, non-stop
Embraer ERJ 145 (ER4)
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  • A domestic route departing from the Knoxville airport (TYS) and arriving at Chicago O'Hare airport (ORD).
  • The flight distance is 475 miles, or 764 km.
  • The timezone of the departure airport is UTC-5 , and the timezone of the arrival airport is UTC-6 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 1:53 and 2:07.