All airlines flying from Chicago O'Hare (ORD) to Knoxville (TYS).

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Daily 09:40 Chicago O'Hare (ORD) 3 12:31 Knoxville (TYS)
American Airlines AA 5202 Non-stop Canadair CRJ 700 (CR7) 1:51 Effective 2026-09-09 through 2026-10-04
Daily 18:36 Chicago O'Hare (ORD) 3 21:23 Knoxville (TYS)
American Airlines AA 5207 Non-stop Canadair CRJ 700 (CR7) 1:47 Effective 2026-08-05 through 2026-09-08
Daily 09:40 Chicago O'Hare (ORD) 3 12:25 Knoxville (TYS)
American Airlines AA 5216 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-08-05 through 2026-09-08
Sat 14:00 Chicago O'Hare (ORD) 3 16:42 Knoxville (TYS)
American Airlines AA 5217 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-02-14 through 2026-03-07
Mon-Sat 08:00 Chicago O'Hare (ORD) 3 10:43 Knoxville (TYS)
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-12 through 2026-03-07
Sun 08:00 Chicago O'Hare (ORD) 3 10:43 Knoxville (TYS)
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-22 through 2026-03-01
Mon,Wed-Sun 08:00 Chicago O'Hare (ORD) 3 10:45 Knoxville (TYS)
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-03-08 through 2026-04-06
Tue 08:05 Chicago O'Hare (ORD) 3 10:50 Knoxville (TYS)
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-03-10 through 2026-03-31
Sun 13:10 Chicago O'Hare (ORD) 3 15:52 Knoxville (TYS)
American Airlines AA 5222 Non-stop Canadair CRJ 700 (CR7) 1:42 Operates only on 2026-02-15
Daily 13:55 Chicago O'Hare (ORD) 3 16:35 Knoxville (TYS)
American Airlines AA 5225 Non-stop Canadair CRJ 700 (CR7) 1:40 Effective 2026-08-05 through 2026-09-08
Mon-Fri,Sun 13:49 Chicago O'Hare (ORD) 3 16:31 Knoxville (TYS)
American Airlines AA 5232 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-03-08 through 2026-04-06
Sat 14:57 Chicago O'Hare (ORD) 3 17:39 Knoxville (TYS)
American Airlines AA 5232 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-03-14 through 2026-04-04
Daily 18:33 Chicago O'Hare (ORD) 3 21:21 Knoxville (TYS)
American Airlines AA 5333 Non-stop Canadair CRJ 700 (CR7) 1:48 Valid until 2026-01-05
Daily 13:10 Chicago O'Hare (ORD) 3 15:52 Knoxville (TYS)
American Airlines AA 5338 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective from 2026-10-05
Daily 18:30 Chicago O'Hare (ORD) 3 21:12 Knoxville (TYS)
American Airlines AA 5341 Non-stop Canadair CRJ 700 (CR7) 1:42 Effective 2026-05-21 through 2026-07-01
Daily 18:30 Chicago O'Hare (ORD) 3 21:17 Knoxville (TYS)
American Airlines AA 5341 Non-stop Canadair CRJ 700 (CR7) 1:47 Effective 2026-07-02 through 2026-08-04
Daily 13:10 Chicago O'Hare (ORD) 3 15:44 Knoxville (TYS)
American Airlines AA 5378 Non-stop Canadair CRJ 700 (CR7) 1:34 Effective 2026-05-21 through 2026-07-01
Daily 13:10 Chicago O'Hare (ORD) 3 15:49 Knoxville (TYS)
American Airlines AA 5378 Non-stop Canadair CRJ 700 (CR7) 1:39 Effective 2026-07-02 through 2026-08-04
Daily 09:40 Chicago O'Hare (ORD) 3 12:19 Knoxville (TYS)
American Airlines AA 5420 Non-stop Canadair CRJ 700 (CR7) 1:39 Effective 2026-07-02 through 2026-08-04
Daily 09:40 Chicago O'Hare (ORD) 3 12:21 Knoxville (TYS)
American Airlines AA 5434 Non-stop Canadair CRJ 700 (CR7) 1:41 Effective 2026-05-21 through 2026-07-01
Sun 18:03 Chicago O'Hare (ORD) 3 20:46 Knoxville (TYS)
American Airlines AA 5454 Non-stop Canadair CRJ 700 (CR7) 1:43 Operates only on 2026-02-15
Mon,Thu,Fri 18:40 Chicago O'Hare (ORD) 3 21:23 Knoxville (TYS)
American Airlines AA 5454 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-12 through 2026-02-20
Mon,Thu,Fri,Sun 18:40 Chicago O'Hare (ORD) 3 21:23 Knoxville (TYS)
American Airlines AA 5454 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-22 through 2026-03-06
Tue,Wed 18:45 Chicago O'Hare (ORD) 3 21:28 Knoxville (TYS)
American Airlines AA 5454 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-17 through 2026-03-04
Mon-Fri,Sun 18:48 Chicago O'Hare (ORD) 3 21:32 Knoxville (TYS)
American Airlines AA 5454 Non-stop Canadair CRJ 700 (CR7) 1:44 Effective 2026-03-08 through 2026-04-06
Daily 11:40 Chicago O'Hare (ORD) 3 14:27 Knoxville (TYS)
American Airlines AA 5467 Non-stop Canadair CRJ 700 (CR7) 1:47 Effective 2026-04-07 through 2026-05-20
Daily 08:00 Chicago O'Hare (ORD) 3 10:46 Knoxville (TYS)
American Airlines AA 5468 Non-stop Canadair CRJ 700 (CR7) 1:46 Effective 2026-04-07 through 2026-05-20
Daily 16:40 Chicago O'Hare (ORD) 3 19:26 Knoxville (TYS)
American Airlines AA 5469 Non-stop Canadair CRJ 700 (CR7) 1:46 Effective 2026-04-07 through 2026-05-20
Tue 13:55 Chicago O'Hare (ORD) 2 16:48 Knoxville (TYS)
United Airlines UA 5588 Non-stop Embraer EMB 175 (E7W) 1:53 Operates only on 2026-02-03
Mon-Fri,Sun 14:00 Chicago O'Hare (ORD) 2 16:53 Knoxville (TYS)
United Airlines UA 5588 Non-stop Canadair CRJ 550 (CR5) 1:53 Effective 2026-01-06 through 2026-02-02
Mon-Fri,Sun 14:00 Chicago O'Hare (ORD) 2 16:53 Knoxville (TYS)
United Airlines UA 5588 Non-stop Canadair CRJ 550 (CR5) 1:53 Effective 2026-02-04 through 2026-02-11
Daily 07:15 Chicago O'Hare (ORD) 2 10:08 Knoxville (TYS)
United Airlines UA 5726 Non-stop Embraer EMB 175 (E7W) 1:53 Effective 2026-03-29 through 2026-05-20
Daily 07:20 Chicago O'Hare (ORD) 2 09:59 Knoxville (TYS)
United Airlines UA 5726 Non-stop Canadair CRJ 550 (CR5) 1:39 Effective from 2026-05-21
Mon-Fri,Sun 07:25 Chicago O'Hare (ORD) 2 10:12 Knoxville (TYS)
United Airlines UA 5726 Non-stop Canadair CRJ (CRJ) 1:47 Effective 2026-02-24 through 2026-03-04
Daily 07:35 Chicago O'Hare (ORD) 2 10:19 Knoxville (TYS)
United Airlines UA 5726 Non-stop Canadair CRJ 550 (CR5) 1:44 Effective 2026-02-12 through 2026-02-23
Thu-Sat 07:35 Chicago O'Hare (ORD) 2 10:19 Knoxville (TYS)
United Airlines UA 5726 Non-stop Canadair CRJ 550 (CR5) 1:44 Effective 2026-02-28 through 2026-03-06
Mon-Fri,Sun 07:35 Chicago O'Hare (ORD) 2 10:19 Knoxville (TYS)
United Airlines UA 5726 Non-stop Canadair CRJ 550 (CR5) 1:44 Effective 2026-03-08 through 2026-03-27
Daily 10:35 Chicago O'Hare (ORD) 2 13:18 Knoxville (TYS)
United Airlines UA 5836 Non-stop Embraer EMB 175 (E7W) 1:43 Effective from 2026-05-21
Direct Codeshare Flights:
Mon-Sat 07:20 Chicago O'Hare (ORD) 2 09:59 Knoxville (TYS)
Avianca AV 2336 Non-stop Canadair CRJ 550 (CR5) 1:39 Effective from 2026-10-26
Codeshare flight, operated by United Airlines.(UA 5726)
Daily 18:00 Chicago O'Hare (ORD) 1 20:45 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A319 (319) 1:45 Effective 2026-04-30 through 2026-05-20
Codeshare flight, operated by United Airlines.(UA 1211)
Daily 18:01 Chicago O'Hare (ORD) 1 20:46 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A319 (319) 1:45 Effective 2026-03-29 through 2026-04-29
Codeshare flight, operated by United Airlines.(UA 1211)
Tue 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A320 (320) 1:42 Operates only on 2026-01-06
Codeshare flight, operated by United Airlines.(UA 1583)
Tue-Sun 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-07 through 2026-01-15
Codeshare flight, operated by United Airlines.(UA 1583)
Wed,Fri 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A320 (320) 1:42 Effective 2026-01-16 through 2026-01-21
Codeshare flight, operated by United Airlines.(UA 1583)
Tue,Thu-Sun 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-17 through 2026-01-27
Codeshare flight, operated by United Airlines.(UA 1583)
Wed-Sat 18:10 Chicago O'Hare (ORD) 1 20:52 Knoxville (TYS)
Avianca AV 2336 Non-stop Airbus A319 (319) 1:42 Effective 2026-01-28 through 2026-01-31
Codeshare flight, operated by United Airlines.(UA 1583)
Tue,Thu-Sun 19:48 Chicago O'Hare (ORD) 2 22:39 Knoxville (TYS)
Avianca AV 2336 Non-stop Canadair CRJ 550 (CR5) 1:51 Valid until 2026-01-04
Codeshare flight, operated by United Airlines.(UA 4575)
Daily 19:50 Chicago O'Hare (ORD) 2 22:35 Knoxville (TYS)
Avianca AV 2336 Non-stop Canadair CRJ 550 (CR5) 1:45 Effective 2026-05-21 through 2026-10-24
Codeshare flight, operated by United Airlines.(UA 4575)
Daily 18:30 Chicago O'Hare (ORD) 3 21:15 Knoxville (TYS)
Qatar Airways QR 2544 Non-stop Canadair CRJ 700 (CR7) 1:45 Effective 2026-09-09 through 2026-10-04
Codeshare flight, operated by American Airlines.(AA 5195)
Thu,Fri 18:40 Chicago O'Hare (ORD) 3 21:23 Knoxville (TYS)
Qatar Airways QR 2583 Non-stop Canadair CRJ 700 (CR7) 1:43 Effective 2026-02-12 through 2026-02-13
Codeshare flight, operated by American Airlines.(AA 5454)
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All airlines flying from Chicago O'Hare (ORD) to Knoxville (TYS).
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:51, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-14 through 2026-03-07
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-12 through 2026-03-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-22 through 2026-03-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
-
Wed
Thu
Fri
Sat
Sun
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-10 through 2026-03-31
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-02-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-08-05 through 2026-09-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:40, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-14 through 2026-04-04
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Valid until 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:48, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective from 2026-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:34, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-07-02 through 2026-08-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-05-21 through 2026-07-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:41, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-02-15
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-12 through 2026-02-20
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-22 through 2026-03-06
Mon
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-02-17 through 2026-03-04
Mon
-
Tue
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-03-08 through 2026-04-06
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:44, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:47, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Effective 2026-04-07 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:46, non-stop
Canadair CRJ 700 (CR7)

Direct Flights:

Operates only on 2026-02-03
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 1:53, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective 2026-01-06 through 2026-02-02
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:53, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-04 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:53, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-29 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:53, non-stop
Embraer EMB 175 (E7W)

Direct Flights:

Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:39, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-24 through 2026-03-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:47, non-stop
Canadair CRJ (CRJ)

Direct Flights:

Effective 2026-02-12 through 2026-02-23
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:44, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-02-28 through 2026-03-06
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 1:44, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective 2026-03-08 through 2026-03-27
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:44, non-stop
Canadair CRJ 550 (CR5)

Direct Flights:

Effective from 2026-05-21
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:43, non-stop
Embraer EMB 175 (E7W)

Direct Codeshare Flights:

Effective from 2026-10-26
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by United Airlines. (UA 5726)
Duration: 1:39, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-04-30 through 2026-05-20
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 1211)
Duration: 1:45, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-03-29 through 2026-04-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 1211)
Duration: 1:45, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Operates only on 2026-01-06
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Codeshare flight, operated by United Airlines. (UA 1583)
Duration: 1:42, non-stop
Airbus A320 (320)

Direct Codeshare Flights:

Effective 2026-01-07 through 2026-01-15
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 1583)
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-01-16 through 2026-01-21
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
-
Codeshare flight, operated by United Airlines. (UA 1583)
Duration: 1:42, non-stop
Airbus A320 (320)

Direct Codeshare Flights:

Effective 2026-01-17 through 2026-01-27
Mon
-
Tue
Wed
-
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 1583)
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Effective 2026-01-28 through 2026-01-31
Mon
-
Tue
-
Wed
Thu
Fri
Sat
Sun
-
Codeshare flight, operated by United Airlines. (UA 1583)
Duration: 1:42, non-stop
Airbus A319 (319)

Direct Codeshare Flights:

Valid until 2026-01-04
Mon
-
Tue
Wed
-
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4575)
Duration: 1:51, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-05-21 through 2026-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by United Airlines. (UA 4575)
Duration: 1:45, non-stop
Canadair CRJ 550 (CR5)

Direct Codeshare Flights:

Effective 2026-09-09 through 2026-10-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by American Airlines. (AA 5195)
Duration: 1:45, non-stop
Canadair CRJ 700 (CR7)

Direct Codeshare Flights:

Effective 2026-02-12 through 2026-02-13
Mon
-
Tue
-
Wed
-
Thu
Fri
Sat
-
Sun
-
Codeshare flight, operated by American Airlines. (AA 5454)
Duration: 1:43, non-stop
Canadair CRJ 700 (CR7)
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  • A domestic route departing from the Chicago O'Hare airport (ORD) and arriving at Knoxville airport (TYS).
  • The flight distance is 475 miles, or 764 km.
  • The timezone of the departure airport is UTC-6 , and the timezone of the arrival airport is UTC-5 . Current time at the point of departure is (loading...), and (loading...) at the point of arrival. There is a (loading...) hour time difference between the airports.
  • For direct flights, the flight time varies between 1:34 and 1:56.